Topical calcipotriol before ablative fractional laser-assisted photodynamic therapy enhances treatment outcomes for actinic keratosis in Fitzpatrick grades III-V skin: A prospective randomized clinical trial
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چکیده
منابع مشابه
Photodynamic Therapy with Ablative Carbon Dioxide Fractional Laser in Treatment of Actinic Keratosis
BACKGROUND Recently, photodynamic therapy (PDT) has been shown to be an effective first-line treatment for actinic keratosis (AK). However, a major limitation of PDT is the long incubation time required to allow penetration of the photosensitizer. OBJECTIVE The aim of this study was to assess if pretreatment with an ablative carbon dioxide (CO2) fractional laser can reduce the incubation time...
متن کاملLong-term Efficacy of Topical Fluorouracil Cream, 5%, for Treating Actinic Keratosis: A Randomized Clinical Trial.
IMPORTANCE Topical fluorouracil was demonstrated to be effective in reducing the number of actinic keratoses (AKs) for up to 6 months, but no randomized trials studied its long-term efficacy. OBJECTIVE To evaluate the long-term efficacy of a single course of fluorouracil cream, 5%, for AK treatment. DESIGN, SETTING, AND PARTICIPANTS The Veterans Affairs Keratinocyte Carcinoma Chemopreventio...
متن کامل308-nm excimer laser plus topical calcipotriol in the treatment of vitiligo; A single blind randomized clinical study
Background: There is a large variety of therapeutic agents for the treatment of vitiligo, but it still remains a challenge. Narrow-band UVB phototherapy and 308-nm excimer laser have been shown to be safe and effective for the treatment of vitiligo. Topical calcipotriol has recently been reported to enhance the efficacy of phototherapy, especially 8-methoxypsoralen plus UVA (PUVA). The goal of ...
متن کاملImportant factors for pain during photodynamic therapy for actinic keratosis.
Photodynamic therapy (PDT) is an efficient treatment for actinic keratosis. A common problem, however, is pain. The aim of this study was to investigate pain during PDT for actinic keratosis. The possibility of using capsaicin cream for pain relief was also assessed. Pain was investigated during aminolaevulinic acid PDT in 91 patients. Size, redness, scaling and induration of the lesions were r...
متن کاملThe medical treatment of the actinic keratosis and the skin tumours: photodynamic therapy (PDT)
Though the experimental studies on the activation of “photodynamic” medications was only published 1999, the FDA approved the use of the ALA (Aminolevulinic) in the dermatologic field. In substance, the PDT by using photosensitive medicines at a topical level (ALA and MAL), a luminous source with an appropriate wavelength for their activation, set the formation of protoporphyrin IX and when it ...
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ژورنال
عنوان ژورنال: Journal of the American Academy of Dermatology
سال: 2018
ISSN: 0190-9622
DOI: 10.1016/j.jaad.2017.11.027